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Effectiveness of Intravenous Iron Treatment vs Standard Care in Patients With Heart Failure and Iron Deficiency: a Randomised, Open-label Multicentre Trial (IRONMAN)

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Trial Profile

Effectiveness of Intravenous Iron Treatment vs Standard Care in Patients With Heart Failure and Iron Deficiency: a Randomised, Open-label Multicentre Trial (IRONMAN)

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 30 Oct 2024

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At a glance

  • Drugs Ferric derisomaltose (Primary)
  • Indications Chronic heart failure; Iron deficiency anaemia; Left ventricular dysfunction
  • Focus Therapeutic Use
  • Acronyms IRONMAN

    • Most Recent Events

    • 02 Sep 2024 Results assessing the effectiveness and cost-utility of FDI compared to usual care for patients with a current or recent HHF, or raised plasma natriuretic peptide concentrations, from a UK National Health Service (NHS) perspective were presented at the ESC Congress 2024 - Annual Congress of the European Society of Cardiology.
    • 29 Aug 2023 According to a Pharmacosmos media release, based on results from this trial the Monofer (ferric derisomaltose) is now recommended in the ESC heart failure guidelines for reducing the risk of hospitalisations for heart failure (Class IIa recommendation) in symptomatic patients with iron deficiency and heart failure (HFrEF & HFmrEF).
    • 07 Nov 2022 Trial design presented at the American Heart Association Scientific Sessions 2022

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