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Study of the Pharmacodynamics of NGM282 on Colonic Transit, Bile Acid Homeostasis, and Fecal Fat in Subjects With Functional Constipation and Healthy Individuals

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Trial Profile

Study of the Pharmacodynamics of NGM282 on Colonic Transit, Bile Acid Homeostasis, and Fecal Fat in Subjects With Functional Constipation and Healthy Individuals

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 09 May 2018

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At a glance

  • Drugs Aldafermin (Primary)
  • Indications Constipation
  • Focus Therapeutic Use
  • Sponsors NGM Biopharmaceuticals

Most Recent Events

  • 02 May 2018 Primary endpoint (Colonic transit as measured by geometric center at 48 h) has been met, according to results published in the American Journal of Gastroenterology.
  • 02 May 2018 Results (n=31) assessing effect of NGM282 on colonic transit, bile acid homeostasis, and fecal fat in subjects with functional constipation and healthy individuals, were published in the American Journal of Gastroenterology.
  • 09 May 2017 Results presented at the Digestive Disease Week 2017

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