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Study of the Pharmacodynamics of NGM282 on Colonic Transit, Bile Acid Homeostasis, and Fecal Fat in Subjects With Functional Constipation and Healthy Individuals

Trial Profile

Study of the Pharmacodynamics of NGM282 on Colonic Transit, Bile Acid Homeostasis, and Fecal Fat in Subjects With Functional Constipation and Healthy Individuals

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 09 May 2018

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At a glance

  • Drugs Aldafermin (Primary)
  • Indications Constipation
  • Focus Therapeutic Use
  • Sponsors NGM Biopharmaceuticals
  • Most Recent Events

    • 02 May 2018 Primary endpoint (Colonic transit as measured by geometric center at 48 h) has been met, according to results published in the American Journal of Gastroenterology.
    • 02 May 2018 Results (n=31) assessing effect of NGM282 on colonic transit, bile acid homeostasis, and fecal fat in subjects with functional constipation and healthy individuals, were published in the American Journal of Gastroenterology.
    • 09 May 2017 Results presented at the Digestive Disease Week 2017
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