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Pleiotropic Effects and Safety of Sodium Glucose Co-transporter 2 Inhibitor Versus Sulfonylurea in Patients With Type 2 Diabetes and Non-alcoholic Fatty Liver

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Trial Profile

Pleiotropic Effects and Safety of Sodium Glucose Co-transporter 2 Inhibitor Versus Sulfonylurea in Patients With Type 2 Diabetes and Non-alcoholic Fatty Liver

Status: Discontinued
Phase of Trial: Phase IV

Latest Information Update: 22 Nov 2024

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At a glance

  • Drugs Tofogliflozin (Primary) ; Glimepiride
  • Indications Non-alcoholic fatty liver disease; Type 2 diabetes mellitus
  • Focus Therapeutic Use

    • Most Recent Events

    • 27 Jul 2022 Primary endpoint (The improvement in histologic features of NAFLD) has been met, according to Results published in the Diabetes Care.
    • 27 Jul 2022 Results published in the Diabetes Care
    • 25 Sep 2020 Results comparing the effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors and sulfo- nylureas, which lower glucose levels with decreases and increases in circulating levels of insulin, respectively, in patients with type 2 diabetespresented at the 56th Annual Meeting of the European Association for the Study of Diabetes

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