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Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure

Trial Profile

Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 27 May 2024

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At a glance

  • Drugs Dapagliflozin (Primary)
  • Indications Chronic heart failure
  • Focus Biomarker; Therapeutic Use
  • Acronyms DEFINE-HF

Most Recent Events

  • 08 Apr 2024 Results (n=233) assessing Relationship Between Inflammatory Biomarkers and Outcomes presented at the 73rd Annual Scientific Session of the American College of Cardiology
  • 13 Nov 2023 Results of Patient-level data were pooled from the DEFINE-HF and PRESERVED-HF presented, at the American Heart Association Scientific Sessions 2023
  • 01 Jul 2023 Results of pooled analysis of DEFINE-HF & PRESERVED-HF assessing effect of dapagliflozin on the change in the Kansas City Cardiomyopathy Questionnaire (KCCQ) Clinical Summary Score (CSS) at 12 weeks was tested with ANCOVA adjusted for sex, baseline KCCQ, EF, atrial fibrillation, estimated glomerular filtration rate, and type 2 diabetes, published in the Circulation: Heart Failure.

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