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A Study of Nivolumab in Combination With Ipilimumab (Part 1); and Nivolumab Plus Ipilimumab in Combination With Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung Cancer (NSCLC)

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Trial Profile

A Study of Nivolumab in Combination With Ipilimumab (Part 1); and Nivolumab Plus Ipilimumab in Combination With Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung Cancer (NSCLC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Apr 2023

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At a glance

  • Drugs Ipilimumab (Primary) ; Nivolumab (Primary)
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms CheckMate 568
  • Sponsors Bristol-Myers Squibb

Most Recent Events

  • 19 Nov 2022 Pooled analysis from CheckMate 227 Part 1, 817 cohort A, 568 Part 1, and 012) assessing OS, PFS, ORR, DOR, and safety published in the Annals of Oncology
  • 29 Aug 2022 Results of pooled analysis form CheckMate 227 Part 1, CheckMate 817 cohort A, CheckMate 568 Part 1 analyzing safety of First-line Nivolumab Plus Ipilimumab in Patients With Metastatic Non-Small Cell Lung Cancer, published in the Journal of Thoracic Oncology
  • 21 Jul 2022 Status changed from active, no longer recruiting to completed.

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