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A Phase 1, Non-Randomized, Open-Label/Phase 2, Randomized, Blinded Study of ProTmune™ (ex Vivo Programmed Mobilized Peripheral Blood Cells) Versus Non-Programmed Mobilized Peripheral Blood Cells for Allogeneic Hematopoietic Cell Transplantation in Adult Subjects With Hematologic Malignancies

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Trial Profile

A Phase 1, Non-Randomized, Open-Label/Phase 2, Randomized, Blinded Study of ProTmune™ (ex Vivo Programmed Mobilized Peripheral Blood Cells) Versus Non-Programmed Mobilized Peripheral Blood Cells for Allogeneic Hematopoietic Cell Transplantation in Adult Subjects With Hematologic Malignancies

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 10 Feb 2023

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At a glance

  • Drugs Programmed cellular immunotherapeutic (Primary)
  • Indications Cytomegalovirus infections; Graft-versus-host disease
  • Focus Adverse reactions; First in man
  • Acronyms PROTECT
  • Sponsors Fate Therapeutics

Most Recent Events

  • 15 Aug 2022 Status changed from active, no longer recruiting to completed.
  • 05 May 2021 Primary endpoint has not been met (Number of patients that experience Grades II-IV acute Graft vs Host Disease (aGvHD)), according to a Fate Therapeutics media release.
  • 04 Mar 2021 Planned End Date changed from 1 Dec 2020 to 1 Dec 2021.

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