A Phase II Trial of the Effect of Perindopril on HFSR Incidence and Severity in Patients Receiving Regorafenib With Refractory Metastatic Colorectal Carcinoma (mCRC)
Latest Information Update: 06 Nov 2021
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At a glance
- Drugs Perindopril (Primary) ; Regorafenib (Primary)
- Indications Adenocarcinoma; Colon cancer; Colorectal cancer; Rectal cancer
- Focus Adverse reactions
- Acronyms PARICCA
- 01 Mar 2019 Status changed to discontinued as at planned interim five of the patients enrolled experienced grade 3 HFSR, as per the published in the Cancer Chemotherapy and Pharmacology.
- 09 Jul 2018 Planned End Date changed from 1 May 2018 to 1 Aug 2018.
- 13 Feb 2018 Planned End Date changed from 1 Jan 2018 to 1 May 2018.