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A Phase I, Double-Blind, Randomized, Placebo-Controlled, Multicenter, Single- and Multiple-Ascending-Dose Study to Determine Initial Safety, Tolerability, and Pharmacokinetics of GDC-0134 in Patients With Amyotrophic Lateral Sclerosis

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A Phase I, Double-Blind, Randomized, Placebo-Controlled, Multicenter, Single- and Multiple-Ascending-Dose Study to Determine Initial Safety, Tolerability, and Pharmacokinetics of GDC-0134 in Patients With Amyotrophic Lateral Sclerosis

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Aug 2020

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At a glance

  • Drugs GDC 0134 (Primary) ; Caffeine; Midazolam; Rabeprazole
  • Indications Amyotrophic lateral sclerosis
  • Focus Adverse reactions; First in man
  • Sponsors Genentech

    • Most Recent Events

    • 04 Aug 2020 Status changed from active, no longer recruiting to completed.
    • 21 Jan 2020 Status changed from recruiting to active, no longer recruiting.
    • 20 Dec 2019 Planned End Date changed from 30 Oct 2019 to 1 Aug 2020.

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