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SGI-110 to potentiate platinum response: a phase Ib/randomised IIa open label clinical trial combining SGI-110 with cisplatin and gemcitabine chemotherapy for solid malignancies including bladder cancer

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Trial Profile

SGI-110 to potentiate platinum response: a phase Ib/randomised IIa open label clinical trial combining SGI-110 with cisplatin and gemcitabine chemotherapy for solid malignancies including bladder cancer

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 07 Jun 2024

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At a glance

  • Drugs Guadecitabine (Primary) ; Cisplatin; Filgrastim; Gemcitabine; Granulocyte colony-stimulating factors
  • Indications Adenocarcinoma; Bladder cancer; Carcinoma; Germ cell cancer; Malignant melanoma; Solid tumours
  • Focus Adverse reactions
  • Acronyms SPIRE

    • Most Recent Events

    • 13 Feb 2021 Results presented at the 2021 Genitourinary Cancers Symposium.
    • 20 Jan 2021 Results published in the Clinical Cancer Research
    • 31 May 2020 Results presented at the 56th Annual Meeting of the American Society of Clinical Oncology

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