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monarcHER: A Phase 2, Randomized, Multicenter, 3-Arm, Open-Label Study to Compare the Efficacy of Abemaciclib Plus Trastuzumab With or Without Fulvestrant to Standard-of-Care Chemotherapy of Physician's Choice Plus Trastuzumab in Women With HR+, HER2+ Locally Advanced or Metastatic Breast Cancer

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monarcHER: A Phase 2, Randomized, Multicenter, 3-Arm, Open-Label Study to Compare the Efficacy of Abemaciclib Plus Trastuzumab With or Without Fulvestrant to Standard-of-Care Chemotherapy of Physician's Choice Plus Trastuzumab in Women With HR+, HER2+ Locally Advanced or Metastatic Breast Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 28 Nov 2024

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At a glance

  • Drugs Abemaciclib (Primary) ; Fulvestrant (Primary) ; Trastuzumab (Primary) ; Antineoplastics
  • Indications Advanced breast cancer; HER2 positive breast cancer
  • Focus Therapeutic Use
  • Acronyms monarcHER
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 18 Mar 2024 Status changed from active, no longer recruiting to completed.
    • 10 Jan 2024 This trial has been completed in Germany, according to European Clinical Trials Database record.
    • 22 Dec 2023 This trial has been completed in Belgium, according to European Clinical Trials Database record.

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