Trial Profile

A Phase 1b/2 Study of Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 20 Jun 2025

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At a glance

Drugs Alvelestat (Primary)
Indications Bronchiolitis obliterans; Graft-versus-host disease
Focus Adverse reactions; Therapeutic Use

Most Recent Events

06 May 2025 Status changed from suspended to recruiting.
04 May 2025 Status changed from recruiting to suspended. (On hold pending an amendment to the study's Principal Investigator.)
13 Jan 2025 Planned primary completion date changed from 1 Dec 2024 to 1 Dec 2027.

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