Hydroxyurea for Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa
Latest Information Update: 07 Nov 2022
At a glance
- Drugs Hydroxycarbamide (Primary)
- Indications Stroke; Transient ischaemic attacks
- Focus Therapeutic Use
- Acronyms SPRINT
- 02 Nov 2022 Results hypothesizing that fixed oral moderate-dose hydroxyurea (20 mg/kg/day) results in an 80% relative risk reduction of stroke or death when compared to fixed oral low-dose hydroxyurea (10 mg/kg/day) in children with sickle cell anemia published in the Blood
- 16 Jan 2022 Status changed from active, no longer recruiting to completed.
- 04 Aug 2021 Planned End Date changed from 1 Jul 2021 to 1 Jul 2022.