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BI 655066 Versus Ustekinumab and Placebo Comparators in a Randomized Double Blind trIal for Maintenance Use in Moderate to Severe Plaque Type Psoriasis-2 (UltIMMa-2)

Trial Profile

BI 655066 Versus Ustekinumab and Placebo Comparators in a Randomized Double Blind trIal for Maintenance Use in Moderate to Severe Plaque Type Psoriasis-2 (UltIMMa-2)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 12 May 2023

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At a glance

  • Drugs Risankizumab (Primary) ; Ustekinumab
  • Indications Plaque psoriasis; Psoriatic arthritis
  • Focus Registrational; Therapeutic Use
  • Acronyms UltIMMa-2
  • Sponsors AbbVie; Boehringer Ingelheim
  • Most Recent Events

    • 21 Mar 2023 Results (n=525 from studies UltIMMa-1, UltIMMa-2 and LIMMitless) assessing the long-term efficacy of RZB in patients with a history of prior biologic use presented at the American Academy of Dermatology annual Meeting 2023
    • 21 Mar 2023 Results assessing the long-term improvement in difficult-to-treat areas (nail, palmoplantar, scalp) and quality of life after switch from ustekinumab (UST) to risankizumab (RZB) in patients with moderate-to-severe plaque psoriasis from UltlMMA-1 and -2 and the open-label LIMMitless extension study, presented at the American Academy of Dermatology annual Meeting 2023.
    • 21 Mar 2023 Results of pooled analysis (n=1306 from four studies UltIMMa-1 and -2, IMMvent, and IMMhance) assessing racial and ethnic diversity for efficacy and safety outcomes presented at the American Academy of Dermatology annual Meeting 2023
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