Trial Profile

Safety, Tolerability and Efficacy of PfSPZ Vaccine Administered by Direct Venous Inoculation (DVI) to Healthy Children and Infants 5 Months Through 9 Years of Age Living in an Area of High Malaria Transmission in Western Kenya: Age De-escalation and Dose Escalation and a Double Blind, Randomized Placebo-Controlled Trial for Safety and Efficacy

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 14 Dec 2021

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At a glance

01 Sep 2021 Results assessing safety, immunogenicity and vaccine efficacy after DVI of PfSPZ Vaccine in 5-12-month-old infants in Kenya, published in the Nature Medicine.
19 May 2020 Results published in the Vaccine
26 Sep 2019 Results assessing safety, tolerability and immunogenicity of various dose regimens of PfSPZ Vaccine published in the Clinical Infectious Diseases

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