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Phase II Study of TGFβ Type I Receptor Inhibitor LY2157299 With Neoadjuvant Chemoradiation in Patients With Locally Advanced Rectal Adenocarcinoma

Trial Profile

Phase II Study of TGFβ Type I Receptor Inhibitor LY2157299 With Neoadjuvant Chemoradiation in Patients With Locally Advanced Rectal Adenocarcinoma

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Jan 2023

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At a glance

  • Drugs Galunisertib (Primary) ; Capecitabine; Fluorouracil; Oxaliplatin
  • Indications Adenocarcinoma; Rectal cancer
  • Focus Therapeutic Use

Most Recent Events

  • 08 Jan 2023 Planned End Date changed from 1 Dec 2022 to 1 Dec 2025.
  • 08 Jan 2023 Planned primary completion date changed from 1 Sep 2022 to 1 Dec 2025.
  • 08 Aug 2022 Results published in the Lancet Oncology

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