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A Randomized Phase III Study to Compare Arsenic Trioxide (ATO) Combined to ATRA and Idarubicin Versus Standard ATRA and Anthracyclines-based Chemotherapy (AIDA Regimen) for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia

Trial Profile

A Randomized Phase III Study to Compare Arsenic Trioxide (ATO) Combined to ATRA and Idarubicin Versus Standard ATRA and Anthracyclines-based Chemotherapy (AIDA Regimen) for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Mar 2025

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At a glance

  • Drugs Arsenic trioxide (Primary) ; Cytarabine; Idarubicin; Mercaptopurine; Methotrexate; Methotrexate; Mitoxantrone; Tretinoin
  • Indications Acute promyelocytic leukaemia
  • Focus Therapeutic Use
  • Acronyms APOLLO

Most Recent Events

  • 26 Feb 2025 Status changed from active, no longer recruiting to completed.
  • 04 Aug 2022 Planned End Date changed from 1 Mar 2025 to 1 Jan 2025.
  • 04 Aug 2022 Planned primary completion date changed from 1 Jul 2022 to 1 Jan 2025.

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