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A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of N91115 for Efficacy and Safety in Patients With CF Heterozygous for F508del-CFTR + Gating Mutation Being Treated With Ivacaftor

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A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of N91115 for Efficacy and Safety in Patients With CF Heterozygous for F508del-CFTR + Gating Mutation Being Treated With Ivacaftor

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 26 Apr 2025

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At a glance

  • Drugs Cavosonstat (Primary) ; Ivacaftor
  • Indications Cystic fibrosis
  • Focus Proof of concept; Therapeutic Use
  • Acronyms SNO-7
  • Sponsors Nivalis Therapeutics

Most Recent Events

  • 25 Jul 2017 According to a Alpine Immune Sciences media release, Alpine Immune Sciences acquired Nivalis Therapeutics and the combined companies changed its name to Alpine Immune Sciences.
  • 01 May 2017 According to a Nivalis Therapeutics media release, following disappointing results of two phase II trials (SNO-6 and SNO-7) of cavosonstat in cystic fibrosis, the company has determined to not pursue the development of this drug in cystic fibrosis and to wind down its research and development activities.
  • 17 Nov 2016 Status changed from recruiting to active, no longer recruiting.

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