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A study to evaluate the effect of P-glycoprotein (P-gp) inhibition with Simeprevir on dose-normalized concentration of calcineurin inhibitors in liver transplant recipients with Hepatitis C

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Trial Profile

A study to evaluate the effect of P-glycoprotein (P-gp) inhibition with Simeprevir on dose-normalized concentration of calcineurin inhibitors in liver transplant recipients with Hepatitis C

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Mar 2016

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At a glance

  • Drugs Simeprevir (Primary) ; Ciclosporin; Sofosbuvir; Tacrolimus
  • Indications Hepatitis C
  • Focus Pharmacodynamics

    • Most Recent Events

    • 14 Mar 2016 New trial record

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