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Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly trabectedin combined with Metronomic Cyclophosphamide in Patients with Advanced Pretreated Soft-tissue Sarcomas. A Phase I/II study from the French Sarcoma Group.

Trial Profile

Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly trabectedin combined with Metronomic Cyclophosphamide in Patients with Advanced Pretreated Soft-tissue Sarcomas. A Phase I/II study from the French Sarcoma Group.

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 13 Dec 2023

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At a glance

  • Drugs Trabectedin (Primary) ; Cyclophosphamide
  • Indications Leiomyosarcoma; Liposarcoma; Soft tissue sarcoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TARMIC

Most Recent Events

  • 24 Oct 2023 Results of the phase II part of the first study (n=30) assessing the trabectedin in combination with metronomic chemotherapy on the tumor microenvironment of patients with advanced sarcomas, presented at the 48th European Society for Medical Oncology Congress.
  • 04 May 2021 Planned End Date changed from 1 Aug 2020 to 1 Aug 2021.
  • 04 May 2021 Planned primary completion date changed from 1 Feb 2020 to 1 Jun 2021.

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