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A Multicenter, Double-Blind, Randomized, Parallel-Group, Placebo-Controlled, Adaptive Dose-Finding Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Subjects With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

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A Multicenter, Double-Blind, Randomized, Parallel-Group, Placebo-Controlled, Adaptive Dose-Finding Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Subjects With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Feb 2025

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At a glance

  • Drugs Seltorexant (Primary)
  • Indications Major depressive disorder
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Janssen Pharmaceutical KK; Janssen Research & Development; Janssen-Cilag

    • Most Recent Events

    • 17 Nov 2021 Results published in the International Journal of Neuropsychopharmacology
    • 29 Jul 2021 Primary endpoint (Primary Efficacy Parameter: Change From Baseline to Week 6 in Montgomery-Asberg Depression Rating Scale (MADRS) Total Score) has not been met, according to Results published in the International Journal of Neuropsychopharmacology.
    • 29 Jul 2021 Results published in the International Journal of Neuropsychopharmacology.

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