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A Phase 1b/2 Dose-Escalation and Cohort-Expansion Study of the Noncovalent, Reversible Bruton's Tyrosine Kinase Inhibitor, SNS-062, in Patients With B-Lymphoid Malignancies

Trial Profile

A Phase 1b/2 Dose-Escalation and Cohort-Expansion Study of the Noncovalent, Reversible Bruton's Tyrosine Kinase Inhibitor, SNS-062, in Patients With B-Lymphoid Malignancies

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Vecabrutinib (Primary)
  • Indications Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Sunesis Pharmaceuticals
  • Most Recent Events

    • 15 Oct 2020 Timepoint for primary outcome measure objective response rate (ORR) and secondary outcome measures changed from 24 months to 36 months.
    • 23 Jun 2020 According to a Sunesis Pharmaceuticals media release, the company will complete the phase 1b portion of this study.
    • 23 Jun 2020 Results presented in a Sunesis Pharmaceuticals media release.

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