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Randomized, Double-Blind, Phase 2 Study of Ramucirumab or Merestinib or Placebo Plus Cisplatin and Gemcitabine as First-Line Treatment in Patients With Advanced or Metastatic Biliary Tract Cancer

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Trial Profile

Randomized, Double-Blind, Phase 2 Study of Ramucirumab or Merestinib or Placebo Plus Cisplatin and Gemcitabine as First-Line Treatment in Patients With Advanced or Metastatic Biliary Tract Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 13 Feb 2025

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At a glance

  • Drugs Merestinib (Primary) ; Ramucirumab (Primary) ; Cisplatin; Gemcitabine
  • Indications Adenocarcinoma; Biliary cancer; Cholangiocarcinoma; Gallbladder cancer; Periampullary cancer
  • Focus Therapeutic Use
  • Sponsors Eli Lilly and Company

Most Recent Events

  • 10 Feb 2025 Planned End Date changed from 31 Dec 2025 to 1 Dec 2025.
  • 17 Jan 2024 Planned End Date changed from 31 Dec 2023 to 31 Dec 2025.
  • 28 Jan 2023 This trial has been discontinued in Italy according to European Clinical Trials Database record.

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