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A Phase 1/2, Open-Label, Dose-Escalation/Dose-Expansion, Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Trial Profile

A Phase 1/2, Open-Label, Dose-Escalation/Dose-Expansion, Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 17 Feb 2025

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At a glance

  • Drugs INCB 057643 (Primary) ; Abiraterone; Azacitidine; Gemcitabine; Paclitaxel; Rucaparib; Ruxolitinib
  • Indications Haematological malignancies; Lymphoma; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Incyte Corporation
  • Most Recent Events

    • 01 Apr 2022 The number of treatment arms increased from 2 to 14.
    • 16 Sep 2019 Results of pooled analysis published in the Clinical Cancer Research.
    • 29 May 2019 Status changed from active, no longer recruiting to discontinued.

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