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A Phase 1b/2 Study to Assess the Safety and Efficacy of HBI-8000 in Combination With Nivolumab in Subjects With Advanced Solid Tumors Including Melanoma, Renal Cell Carcinoma (RCC), and Non-Small Cell Lung Cancer (NSCLC)

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Trial Profile

A Phase 1b/2 Study to Assess the Safety and Efficacy of HBI-8000 in Combination With Nivolumab in Subjects With Advanced Solid Tumors Including Melanoma, Renal Cell Carcinoma (RCC), and Non-Small Cell Lung Cancer (NSCLC)

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 14 Nov 2024

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At a glance

  • Drugs Nivolumab (Primary) ; Tucidinostat (Primary)
  • Indications Malignant melanoma; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours
  • Focus Adverse reactions
  • Sponsors HUYA Bioscience International

    • Most Recent Events

    • 08 Nov 2024 According to a HUYA Bioscience International media release, data from this trial will be presented at the Society for Immunotherapy of Cancer (SITC) 2024 Annual Meeting
    • 08 Nov 2024 Results from the final analysis of phase 2 study evaluating HBI-8000 in combination with nivolumab (anti-PD1 therapy), a novel combination for the treatment of advanced and metastatic melanoma presented in the HUYABIO Media Release
    • 08 Nov 2023 Status changed from active, no longer recruiting to completed.

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