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A Phase 1/2 Open-label Safety and Dose-finding Study of BAY2599023 (DTX201), an Adeno-associated Virus (AAV) hu37-mediated Gene Transfer of B-domain Deleted Human Factor VIII, in Adults With Severe Hemophilia A

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Trial Profile

A Phase 1/2 Open-label Safety and Dose-finding Study of BAY2599023 (DTX201), an Adeno-associated Virus (AAV) hu37-mediated Gene Transfer of B-domain Deleted Human Factor VIII, in Adults With Severe Hemophilia A

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 08 Feb 2025

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At a glance

  • Drugs Peboctocogene camaparvovec (Primary)
  • Indications Haemophilia A
  • Focus Adverse reactions; First in man
  • Acronyms Get8; Shuttle
  • Sponsors Bayer; Dimension Therapeutics
  • Most Recent Events

    • 16 Dec 2024 Planned End Date changed from 30 Nov 2026 to 3 Nov 2026.
    • 12 Sep 2022 Status changed from recruiting to active, no longer recruiting.
    • 07 Aug 2022 Planned End Date changed from 28 Jun 2027 to 30 Nov 2026.

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