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A Phase I Clinical Trial for the Treatment of ß-Thalassemia Major With Autologous CD34+ Hematopoietic Progenitor Cells Transduced With TNS9.3.55 a Lentiviral Vector Encoding the Normal Human ß-Globin Gene

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A Phase I Clinical Trial for the Treatment of ß-Thalassemia Major With Autologous CD34+ Hematopoietic Progenitor Cells Transduced With TNS9.3.55 a Lentiviral Vector Encoding the Normal Human ß-Globin Gene

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Sep 2024

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At a glance

  • Drugs Beta-globin-transduced bone marrow cells (Primary) ; Busulfan; Filgrastim
  • Indications Beta-thalassaemia
  • Focus Adverse reactions

    • Most Recent Events

    • 06 Aug 2024 Planned End Date changed from 1 Jul 2024 to 1 Jul 2025.
    • 06 Aug 2024 Planned primary completion date changed from 1 Jul 2024 to 1 Jul 2025.
    • 11 Jul 2023 Planned End Date changed from 1 Jul 2023 to 1 Jul 2024.

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