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A Phase III Randomized Open-label Multi-center Study of Ruxolitinib Versus Best Available Therapy in Patients With Corticosteroid-refractory Acute Graft vs. Host Disease After Allogeneic Stem Cell Transplantation

Trial Profile

A Phase III Randomized Open-label Multi-center Study of Ruxolitinib Versus Best Available Therapy in Patients With Corticosteroid-refractory Acute Graft vs. Host Disease After Allogeneic Stem Cell Transplantation

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 19 Jul 2024

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At a glance

  • Drugs Ruxolitinib (Primary)
  • Indications Graft-versus-host disease
  • Focus Registrational; Therapeutic Use
  • Acronyms REACH2
  • Sponsors Novartis; Novartis Pharmaceuticals
  • Most Recent Events

    • 01 Jul 2024 Results assessing efficacy and safety findings of ruxolitinib versus best available therapy (BAT) from a subgroup analysis published in the International Journal of Hematology
    • 21 Mar 2023 Results of post hoc analysis from REACH2 and REACH3 trials assessing the ruxolitinib efficacy in patients with dermatologic manifestations of graft-versus-host disease, presented at the American Academy of Dermatology annual Meeting 2023.
    • 06 Mar 2023 According to Incyte Media Release, A Post Hoc Analysis of the Phase 3 REACH2 and REACH3 Studies will be presented at the upcoming 2023 American Academy of Dermatology (AAD) Annual Meeting

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