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A Phase 2, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group, Study to Investigate the Safety and Tolerability of Multiple Dose Administration of CSL112 in Subjects With Moderate Renal Impairment and Acute Myocardial Infarction

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Trial Profile

A Phase 2, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group, Study to Investigate the Safety and Tolerability of Multiple Dose Administration of CSL112 in Subjects With Moderate Renal Impairment and Acute Myocardial Infarction

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 11 Oct 2023

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At a glance

  • Drugs CSL 112 (Primary)
  • Indications Myocardial ischaemia
  • Focus Adverse reactions
  • Sponsors CSL Behring

    • Most Recent Events

    • 28 Aug 2023 Results assessing whether infusion of CSL112 inhibits post-AMI inflammation as measured by NLR presented at the ESC Congress 2023 - Annual Congress of the European Society of Cardiology
    • 12 Mar 2018 Results (n=83) assessing renal safety and tolerability of multiple dose intravenous (IV) administration of CSL112 compared with placebo in subjects with moderate renal impairment (RI) and acute myocardial infarction (AMI), were presented at the 67th Annual Scientific Session of the American College of Cardiology.
    • 07 Jul 2017 Status changed from active, no longer recruiting to completed.

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