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This drug-drug interaction trial to investigate the pharmacokinetics and predict QTcF interval prolongation of naloxegol with ketoconazole in healthy volunteers

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Trial Profile

This drug-drug interaction trial to investigate the pharmacokinetics and predict QTcF interval prolongation of naloxegol with ketoconazole in healthy volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 21 Apr 2016

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At a glance

  • Drugs Naloxegol (Primary) ; Ketoconazole
  • Indications Constipation
  • Focus Pharmacokinetics
  • Acronyms TQT study
  • Sponsors AstraZeneca

Most Recent Events

  • 21 Apr 2016 New trial record
  • 12 Mar 2016 Results of QT analysis (n=47) presented at the 117th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics.

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