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Phase 2b/3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Dipraglurant (ADX48621) for the Treatment of Dyskinesia in Patients With Parkinson's Disease Receiving Levodopa-based Therapy

Trial Profile

Phase 2b/3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Dipraglurant (ADX48621) for the Treatment of Dyskinesia in Patients With Parkinson's Disease Receiving Levodopa-based Therapy

Status: Discontinued
Phase of Trial: Phase II/III

Latest Information Update: 23 Jun 2022

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At a glance

  • Drugs Dipraglurant (Primary)
  • Indications Drug-induced dyskinesia
  • Focus Registrational; Therapeutic Use
  • Sponsors Addex Therapeutics
  • Most Recent Events

    • 17 Jun 2022 Status changed from recruiting to discontinued.
    • 17 Jun 2022 According to Addex Therapeutics media release, the company has announced the termination of this study for the treatment of dyskinesia associated with Parkinson's disease due to slow recruitment of patients. The slow recruitment of the patients was due to the consequences of COVID-19 related patient concerns about participation in the study as well as human resource shortages.
    • 10 Mar 2022 According to an Addex Therapeutics media release, data from this study is expected in H1 2023.
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