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A three part, randomised, double-blind, placebo-controlled single ascending dose study to assess safety, pharmacokinetics and pharmacodynamics of oral HTL0018318 in healthy younger adult and elderly subjects.

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A three part, randomised, double-blind, placebo-controlled single ascending dose study to assess safety, pharmacokinetics and pharmacodynamics of oral HTL0018318 in healthy younger adult and elderly subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 30 Dec 2020

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At a glance

  • Drugs HTL 18318 (Primary)
  • Indications Alzheimer's disease; Cognition disorders; Dementia
  • Focus Adverse reactions; First in man; Pharmacodynamics; Pharmacokinetics
  • Sponsors Heptares Therapeutics

    • Most Recent Events

    • 22 Dec 2020 Results published in the British Journal of Clinical Pharmacology
    • 05 Aug 2017 Status changed from recruiting to completed.
    • 10 May 2016 New trial record

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