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A Phase 2 Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of Pegylated Interferon Lambda Monotherapy in Patients With Chronic Hepatitis Delta Virus Infection (LIMT)

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Trial Profile

A Phase 2 Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of Pegylated Interferon Lambda Monotherapy in Patients With Chronic Hepatitis Delta Virus Infection (LIMT)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 01 Jan 2024

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At a glance

  • Drugs Peginterferon lambda-1a (Primary)
  • Indications Hepatitis D
  • Focus Therapeutic Use
  • Acronyms LIMT; LIMT HDV; LIMT-1
  • Sponsors Eiger BioPharmaceuticals

Most Recent Events

  • 14 Nov 2023 Results of pooled analysis from LOWR-3 , LIMT-1 and LIFT-1, comparing different combinations of novel HDV therapies and assessing their anti-HDV effectiveness, presented at The Liver Meeting 2023: 74th Annual Meeting of the American Association for the Study of Liver Diseases
  • 14 Nov 2023 Results assessing the predict Lambda mechanisms of action and efficacy using mathematical modeling of measured HDV RNA, ALT and HBsAg kinetics, presented at The Liver Meeting 2023: 74th Annual Meeting of the American Association for the Study of Liver Diseases.
  • 20 Feb 2023 Results assessing the safety and efficacy of Lambda monotherapy in patients with chronic hepatitis delta virus, published in the Hepatology.

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