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Candidate Therapies in Combination or Sequentially With Tyrosine Kinase Inhibitors in Chronic Phase-chronic Myelogenous Leukemia Patients in CCR Without Achieving a Deep Molecular Response: an Adaptative Trial Based on a Drop Loser Design

Trial Profile

Candidate Therapies in Combination or Sequentially With Tyrosine Kinase Inhibitors in Chronic Phase-chronic Myelogenous Leukemia Patients in CCR Without Achieving a Deep Molecular Response: an Adaptative Trial Based on a Drop Loser Design

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 24 Sep 2024

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At a glance

  • Drugs Avelumab (Primary) ; Pioglitazone (Primary) ; Bosutinib; Dasatinib; Imatinib; Nilotinib; Ponatinib
  • Indications Chronic myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms ACTIW

Most Recent Events

  • 06 Aug 2020 Planned End Date changed from 1 Jun 2021 to 1 Jun 2023.
  • 06 Aug 2020 Planned primary completion date changed from 1 Jun 2019 to 1 Nov 2022.
  • 23 May 2018 Avelumab has been added in the treatments.

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