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A Phase 1-2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-C19 in Combination With Atezolizumab in Subjects With Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

Trial Profile

A Phase 1-2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-C19 in Combination With Atezolizumab in Subjects With Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 13 Mar 2024

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At a glance

  • Drugs Axicabtagene ciloleucel (Primary) ; Atezolizumab; Cyclophosphamide; Fludarabine
  • Indications Diffuse large B cell lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ZUMA-6
  • Sponsors Kite Pharma

Most Recent Events

  • 13 Feb 2024 Number of treatment arms are increased from 1 to 4 by the addition of separate arms for 2 more cohorts in Phase 1 part and an arm for the phase 2 part.
  • 31 Jan 2023 Status changed from active, no longer recruiting to completed.
  • 18 Nov 2022 Planned End Date changed from 1 Sep 2022 to 1 Dec 2022.

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