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A Phase 1, Open-label, 2-period Fixed-sequence Study to Evaluate the Effect of Multiple Doses of SHP620 (Maribavir) on the Pharmacokinetics of Digoxin and Dextromethorphan in Healthy Adult Subjects

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Trial Profile

A Phase 1, Open-label, 2-period Fixed-sequence Study to Evaluate the Effect of Multiple Doses of SHP620 (Maribavir) on the Pharmacokinetics of Digoxin and Dextromethorphan in Healthy Adult Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Maribavir (Primary) ; Dextromethorphan; Digoxin
  • Indications Cytomegalovirus infections
  • Focus Pharmacokinetics
  • Sponsors Shire

Most Recent Events

  • 06 Aug 2019 Results assessing the effects of multiple oral doses of maribavir on CYP2D6 and P-gp activity in healthy adults by assessing the plasma, PK profile of the probe drugs published in the Journal of Clinical Pharmacology
  • 20 Sep 2016 Status changed from recruiting to completed.
  • 24 Aug 2016 Status changed from not yet recruiting to recruiting.

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