Trial Profile

An Open-Label, Randomized, Multicentre, Phase 2 Study of FOLFIRI + Bevacizumab + Pelareorep vs. FOLFIRI + Bevacizumab for the Second-Line Treatment of Metastatic, RAS-mutated, Microsatellite-Stable (MSS) Colorectal Cancer

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 11 Mar 2026

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At a glance

Drugs Bevacizumab (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Pelareorep (Primary) ; Pembrolizumab
Indications Colorectal cancer
Focus Therapeutic Use

02 Mar 2026 According to an Oncolytics Biotech media release,The Company is expecting to initiate the first study site later this month and provide preliminary data by year-end.
02 Mar 2026 Status changed from not yet recruiting to recruiting.
29 Jun 2016 According to an Oncolytics Biotech media release, the IND application to US FDA containing protocol for this trial is now active.

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