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Perioperative Systemic Therapy and Cytoreductive Surgery With HIPEC Versus Upfront Cytoreductive Surgery With HIPEC Alone for Isolated Resectable Colorectal Peritoneal Metastases: a Multicentre, Open-label, Parallel-group, Phase II-III, Randomised Superiority Study

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Perioperative Systemic Therapy and Cytoreductive Surgery With HIPEC Versus Upfront Cytoreductive Surgery With HIPEC Alone for Isolated Resectable Colorectal Peritoneal Metastases: a Multicentre, Open-label, Parallel-group, Phase II-III, Randomised Superiority Study

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 29 Aug 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Capecitabine; Fluorouracil; Folinic acid; Irinotecan; Mitomycin; Oxaliplatin
  • Indications Adenocarcinoma; Cancer metastases; Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms CAIRO-6

    • Most Recent Events

    • 22 Aug 2024 Planned End Date changed from 1 Aug 2026 to 1 Jun 2029.
    • 22 Aug 2024 Planned primary completion date changed from 1 Aug 2024 to 1 Dec 2025.
    • 03 Aug 2021 Status changed from recruiting to active, no longer recruiting.

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