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A Proof of Concept, Open-Label Study Evaluating the Safety, Tolerability, and Efficacy of Regimens in Subjects With Hepatic Steatosis and Elevated Liver Stiffness

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Trial Profile

A Proof of Concept, Open-Label Study Evaluating the Safety, Tolerability, and Efficacy of Regimens in Subjects With Hepatic Steatosis and Elevated Liver Stiffness

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Mar 2022

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At a glance

  • Drugs Cilofexor (Primary) ; Ethyl eicosapentaenoic acid (Primary) ; Fenofibrate (Primary) ; Firsocostat (Primary) ; Selonsertib (Primary)
  • Indications Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis
  • Focus Adverse reactions; Proof of concept
  • Sponsors Gilead Sciences

    • Most Recent Events

    • 26 Jun 2021 Results evaluating the safety and efficacy of fenofibrate (FENO) and icosapent ethyl (Vascepa , VAS) to mitigate increases in serum triglycerides (TG) in NASH patients treated with CILO+FIR presented at The International Liver Congress 2021
    • 14 Jan 2021 Status changed from active, no longer recruiting to completed.
    • 26 Oct 2020 Status changed from recruiting to active, no longer recruiting.

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