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A Phase 1/1b, Open-label Study of Pevonedistat (MLN4924, TAK-924) as Single Agent and in Combination With Azacitidine in Adult East Asian Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS)

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A Phase 1/1b, Open-label Study of Pevonedistat (MLN4924, TAK-924) as Single Agent and in Combination With Azacitidine in Adult East Asian Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2023

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At a glance

  • Drugs Pevonedistat (Primary) ; Azacitidine; Azacitidine
  • Indications Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Takeda Oncology

    • Most Recent Events

    • 14 Mar 2022 Status changed from active, no longer recruiting to completed.
    • 20 Jan 2022 Planned End Date changed from 31 Dec 2021 to 25 Jan 2022.
    • 20 Jan 2022 Planned primary completion date changed from 31 Dec 2021 to 25 Jan 2022.

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