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A Phase 1 Dose Escalation Trial to Assess the Safety and Efficacy of Infectious (Replication-intact), Cryopreserved Plasmodium Falciparum Sporozoites (PfSPZ Challenge) Administered by Direct Venous Inoculation Under Chloroquine Cover (PfSPZ-CVac) on Varying Schedules in Healthy Malaria-Naïve Adults in the United States

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A Phase 1 Dose Escalation Trial to Assess the Safety and Efficacy of Infectious (Replication-intact), Cryopreserved Plasmodium Falciparum Sporozoites (PfSPZ Challenge) Administered by Direct Venous Inoculation Under Chloroquine Cover (PfSPZ-CVac) on Varying Schedules in Healthy Malaria-Naïve Adults in the United States

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 30 Dec 2019

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At a glance

  • Drugs Malaria vaccine live unattenuated-Sanaria (Primary)
  • Indications Falciparum malaria
  • Focus Adverse reactions

    • Most Recent Events

    • 08 Feb 2018 Status changed from active, no longer recruiting to completed.
    • 09 Nov 2017 Planned End Date changed from 30 Sep 2017 to 25 Jan 2018.
    • 09 Nov 2017 Planned primary completion date changed from 30 Sep 2017 to 25 Jan 2018.

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