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Non-randomized, prospective, non-controlled study of changes of lipid parameters after introduction of evolocumab in patients with heterozygous familial hypercholesterolemia under LDL-apheresis therapy.

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Trial Profile

Non-randomized, prospective, non-controlled study of changes of lipid parameters after introduction of evolocumab in patients with heterozygous familial hypercholesterolemia under LDL-apheresis therapy.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Feb 2020

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At a glance

  • Drugs Evolocumab (Primary)
  • Indications Hyperlipoproteinaemia type IIa
  • Focus Therapeutic Use

    • Most Recent Events

    • 30 Aug 2017 Primary endpoint (Comparison of the time constant average levels of LDL-C and apoB during LDL-apheresis and those under evolocumab thereapy.) has been met as per the results presented at the ESC Congress 2017: Annual Congress of the European Society of Cardiology
    • 30 Aug 2017 Results presented at the ESC Congress 2017: Annual Congress of the European Society of Cardiology
    • 08 Dec 2016 Status changed from recruiting to completed.

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