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A Phase 1, Open-Label, Drug-Interaction Study to Evaluate the Effect of Clarithromycin, a Potent CYP3A4 Inhibitor, on the Systemic Exposure of Pacritinib in Healthy Subjects

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Trial Profile

A Phase 1, Open-Label, Drug-Interaction Study to Evaluate the Effect of Clarithromycin, a Potent CYP3A4 Inhibitor, on the Systemic Exposure of Pacritinib in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Pacritinib (Primary) ; Clarithromycin
  • Indications Acute myeloid leukaemia; Chronic myeloid leukaemia; Colorectal cancer; Haematological disorders; Myelodysplastic syndromes; Myelofibrosis; Myeloproliferative disorders
  • Focus Pharmacokinetics
  • Sponsors CTI BioPharma

    • Most Recent Events

    • 25 Jun 2016 New trial record

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