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Pharmacokinetic drug-drug interaction study between oral 300 mg netupitant/0.50 mg palonosetron fixed dose combination (Akynzeo®) and oral dexamethasone. Evaluation of the duration of the CYP3A4 inhibition in a randomized, two-period, two-sequence, crossover study in healthy subjects

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Pharmacokinetic drug-drug interaction study between oral 300 mg netupitant/0.50 mg palonosetron fixed dose combination (Akynzeo®) and oral dexamethasone. Evaluation of the duration of the CYP3A4 inhibition in a randomized, two-period, two-sequence, crossover study in healthy subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Jul 2016

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At a glance

  • Drugs Netupitant/palonosetron (Primary) ; Dexamethasone
  • Indications Chemotherapy-induced nausea and vomiting
  • Focus Pharmacokinetics
  • Sponsors Helsinn Healthcare SA

    • Most Recent Events

    • 05 Jul 2016 New trial record

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