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A Phase II Trial of CD24Fc for Prevention of Acute Graft-versus-Host Disease Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplant

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Trial Profile

A Phase II Trial of CD24Fc for Prevention of Acute Graft-versus-Host Disease Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplant

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 13 Dec 2023

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At a glance

  • Drugs Efprezimod alfa (Primary) ; Methotrexate; Tacrolimus; Tacrolimus
  • Indications Graft-versus-host disease
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Sponsors OncoImmune
  • Most Recent Events

    • 30 Aug 2023 Primary endpoint has been met, (Open Label Expansion Arm Only: Grade III-IV Acute Graft-Versus-Host Disease (GVHD) Free Survival (AGFS), as per Results published in the Blood
    • 30 Aug 2023 Results published in the Blood
    • 23 Apr 2021 Planned End Date changed from 30 Apr 2021 to 5 May 2021.

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