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Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

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Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Mar 2025

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At a glance

  • Drugs Antithymocyte globulin (Primary) ; Blinatumomab (Primary) ; Cyclophosphamide (Primary) ; Filgrastim (Primary) ; Filgrastim (Primary) ; Fludarabine (Primary) ; Melphalan (Primary) ; Mesna (Primary) ; Rituximab (Primary) ; Tacrolimus (Primary) ; Tacrolimus (Primary) ; Thiotepa (Primary)
  • Indications Haematological malignancies; Lymphoid leukaemia; Myelodysplastic syndromes; Myeloid leukaemia; Non-Hodgkin's lymphoma; Sarcoma
  • Focus Therapeutic Use

    • Most Recent Events

    • 09 Oct 2024 Status changed from recruiting to active, no longer recruiting.
    • 05 Aug 2024 Planned End Date changed from 1 Jul 2025 to 1 Jul 2026.
    • 05 Aug 2024 Planned primary completion date changed from 1 Jul 2024 to 1 Jul 2025.

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