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Efficacy and Safety of Oral Semaglutide versus Empagliflozin in Subjects with Type 2 Diabetes Mellitus. A 52-week Randomised, Open-label, Active-controlled Trial

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Trial Profile

Efficacy and Safety of Oral Semaglutide versus Empagliflozin in Subjects with Type 2 Diabetes Mellitus. A 52-week Randomised, Open-label, Active-controlled Trial

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Jun 2023

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At a glance

  • Drugs Semaglutide (Primary) ; Empagliflozin
  • Indications Type 2 diabetes mellitus
  • Focus Registrational; Therapeutic Use
  • Acronyms PIONEER 2
  • Sponsors Novo Nordisk

Most Recent Events

  • 31 May 2023 Results of a post-hoc analysis from clinical trials: PIONEER 1-5 and 8 assessing clinically relevant composite endpoints of HbA1c (glyclated haemogloblin) reduction published in the Diabetes Therapy
  • 23 Sep 2022 Results of an exploratory analysis assessing time spent by patients with HbA1c <7.0% (53 mmol/mol), and likelihood of maintaining this glycaemic control using data from four clinical studies: PIONEER-2, PIONEER-3, PIONEER-4 and PIONEER-7 presented at the 58th Annual Meeting of the European Association for the Study of Diabetes
  • 12 May 2022 Results evaluating Cost-Effectiveness of Oral Semaglutide in Spain by deriving data from PIONEER 2, PIONEER 3 and PIONEER 4, published in the Advances in Therapy

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