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A Phase 1, First-in-Human, Double-blinded, Randomized, Placebo-controlled Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of an Alum Adjuvanted Zika Virus Purified Inactivated Vaccine (ZPIV) in Healthy Flavivirus-Naïve and Flavivirus-Primed Subjects

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A Phase 1, First-in-Human, Double-blinded, Randomized, Placebo-controlled Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of an Alum Adjuvanted Zika Virus Purified Inactivated Vaccine (ZPIV) in Healthy Flavivirus-Naïve and Flavivirus-Primed Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 16 Jun 2020

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At a glance

  • Drugs Zika virus vaccine-Sanofi (Primary) ; IC 51; Yellow fever vaccine
  • Indications Zika virus infection
  • Focus Adverse reactions; First in man

    • Most Recent Events

    • 12 May 2020 Results presented at the IMMUNOLOGY 2020: American Association of Immunologists Annual Meeting
    • 08 Nov 2018 Status changed from active, no longer recruiting to completed.
    • 05 Dec 2017 Preliminary results assessing the early safety and immunogenicity of Zika-virus-vaccine in the phase I trials (NCT02963909, NCT02952833, and NCT02937233; n=68) published in The Lancet.

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