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A Phase 1b Study of Safety and Immune Response to PVX-410 Vaccine Alone and in Combination with Durvalumab in Human Leukocyte Antigen (HLA)-A2+ Subjects Following Standard Treatment of Stage II or III Triple Negative Breast Cancer

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Trial Profile

A Phase 1b Study of Safety and Immune Response to PVX-410 Vaccine Alone and in Combination with Durvalumab in Human Leukocyte Antigen (HLA)-A2+ Subjects Following Standard Treatment of Stage II or III Triple Negative Breast Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 30 Sep 2024

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At a glance

  • Drugs PVX 410 (Primary) ; Durvalumab; Poly ICLC
  • Indications Advanced breast cancer; Early breast cancer; Triple negative breast cancer
  • Focus Adverse reactions
  • Most Recent Events

    • 23 Sep 2024 Planned End Date changed from 1 Sep 2025 to 1 Sep 2026.
    • 23 Sep 2024 Planned primary completion date changed from 1 Jun 2024 to 1 Jun 2025.
    • 13 Nov 2023 Planned End Date changed from 1 Sep 2023 to 1 Sep 2025.

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