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A Phase 1, Open-Label Study of the Safety, Pharmacokinetics and Pharmacodynamics of JNJ-64457107, an Agonistic Human Monoclonal Antibody Targeting CD40 in Patients With Advanced Stage Solid Tumors

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Trial Profile

A Phase 1, Open-Label Study of the Safety, Pharmacokinetics and Pharmacodynamics of JNJ-64457107, an Agonistic Human Monoclonal Antibody Targeting CD40 in Patients With Advanced Stage Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 11 Oct 2023

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At a glance

  • Drugs Mitazalimab (Primary)
  • Indications Malignant melanoma; Non-small cell lung cancer; Pancreatic cancer; Renal cell carcinoma; Solid tumours
  • Focus Adverse reactions
  • Sponsors Janssen Biotech; Janssen Research & Development

    • Most Recent Events

    • 27 Sep 2023 According to an Alligator Bioscience media release, results presented at the AACR Pancreatic 2023 conference on Thursday, September 28
    • 27 Sep 2023 According to an Alligator Bioscience media release, the publication of pharmacodynamic data in a scientific article from a phase 1 dose escalation part in patients with advanced solid tumors
    • 10 Feb 2023 According to an Alligator Bioscience media release, results from this study were presented at the SITC Annual Meeting 2022.

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